I remember Wizard Magazine did an article on this particular match up, except it was ALL of the Flash's rogues versus ALL of Spider-Man's villains....and Wizard decided DC would've won it.
I disagreed then, and I still disagree now.
That's why I'm doing this my way, and pitting the definitive versions of both of villain teams against each other in a fight to the death. That's right a fight to the death.
I know the Rogues have their own code when it comes to killing, as far as they only do it when they absolutely have to, and when it's out of vengeance/revenge.
I also know the Sinister Six, any variation of the Sinister Six, is more lax about killing, and usually go for the kill against whoever it is they're after, ESPECIALLY Spider-Man.
So, that being said, I'm going to make things easy on myself and only use original members only.
Here's how they stack up:
-The (original) Sinister Six:
1). Doctor Octopus
| Abilities | (As Doctor Octopus/Superior Octopus):
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2). The Vulture
| Abilities | Genius electrical engineer Electromagnetic tailored body-harness grants: Enhanced physical attributes Flight |
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3). Electro
| Abilities |
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4). Sandman
| Abilities | Size and mass manipulation Shapeshifting Earth manipulation Superhuman strength, durability and endurance Density control Flight (in sandstorm form) |
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5). Kraven the Hunter
| Abilities |
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6). Mysterio
| Abilities |
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-The Rogues:

1). Captain Cold
| Abilities | Master tactician, Master Thief and strategist Extensive knowledge of cryonics Skilled marksman Possesses a 'cold gun' that allows him to freeze objects to absolute zero temperatures |
|---|
2). Mirror Master
| Abilities | Various powers over mirrors, including the ability to travel through them and trap others within them. |
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3). Heatwave
| Abilities | Possesses a handgun sized flamethrower and knowledge of pyrotechnics and combustibles Wears an asbestos suit that protects him from fire and heat Pipe attached to his left arm that allows him to put out fires |
|---|
4). Captain Boomerang
5). Weather Wizard
| Abilities | Weather manipulation via weather wand Limited magnetic manipulation |
|---|
6). The Trickster
| Abilities | (Jesse) Skilled acrobat and con-artist Above-average intelligence (Both) Gadgets that give him the ability to perform amazing tricks like walking on air |
|---|
Now of course I had to leave some members of the Rogues out of this to make it a fair fight, otherwise, The Pied Piper and The Top would be in this as well.
But again, for the sake of fairness, I chose to keep it a strictly 6-on-6 fight to the finish with no advantages in the numbers' department.
And there it is.
A fight to the bitter end between two very famous/infamous teams of supervillains, battling it out for bragging rights.
So,
The Sinister Six




VS.
The Rogues


Let me know who you think are the last rogues standing after all's said and done.




















